Autoimmune disease
Pentad of Symptoms
- Neurology: Headache, confusion, seizure
- Renal Failure
- Fever
- Thrombocytopenia
- Microangiopathic haemolysis
Diagnosis
Clinically
Bloods
- Blood film (fragmented red cells, reticulocytes, schistocytes)
- evidence of renal failure
- evidence of haemolysis (low Hb, high AP)